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Impact of Machine Learning on Drug Demand Forecasting in Pharmaceutical Supply Chains

Research articleOpen accessVol. 13, Issue 4, March 2025

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Abstract

The pharmaceutical industry is characterized by its complex supply chains, critical product demand, and life‐saving inventory management requirements. This paper investigates the impact of machine learning (ML) techniques on drug demand forecasting—a crucial component for optimizing inventory levels, reducing wastage, and ensuring timely distribution of medications. By integrating historical sales data, seasonality trends, socio-economic indicators, and health data, ML algorithms provide a dynamic and accurate forecasting model. This study reviews literature up to 2018, introduces a novel methodology incorporating ensemble learning and time-series analysis, and evaluates the model against traditional forecasting methods. The findings indicate that ML-based approaches significantly improve forecasting accuracy, reduce supply chain disruptions, and support better decision-making in pharmaceutical logistics. The implications of this research suggest that the adoption of advanced ML techniques can lead to enhanced operational efficiency and improved patient outcomes.

Keywords: Machine Learning, Drug Demand Forecasting, Pharmaceutical Supply Chain, Predictive Analytics, Artificial Intelligence

References

  • https://www.google.com/url?sa=i&url=https%3A%2F%2Fwww.techtarget.com%2Fpharmalifesciences%2Ffeature%2FFundamentals-of-the-Pharmaceutical-Supply-Chain&psig=AOvVaw2II2FRvxfuFy_9ip32KWQ-&ust=1740580047339000&source=images&cd=vfe&opi=89978449&ved=0CBQQjRxqFwoTCJio442E34sDFQAAAAAdAAAAABAJ
  • https://www.google.com/url?sa=i&url=https%3A%2F%2Fspotintelligence.com%2F2024%2F05%2F06%2Fsupport-vector-machines-svm%2F&psig=AOvVaw1VO_2JE9R_lRcbpmXPmegm&ust=1740581651661000&source=images&cd=vfe&opi=89978449&ved=0CBQQjRxqFwoTCICxjIqK34sDFQAAAAAdAAAAABAE
  • Armstrong, J. S. (Ed.). (2001). Principles of Forecasting: A Handbook for Researchers and Practitioners. Kluwer Academic Publishers.
  • Box, G. E. P., & Jenkins, G. M. (1976). Time Series Analysis: Forecasting and Control. Holden-Day.
  • Brezin, G. P., Patuwo, B. E., & Hu, M. Y. (1998). Forecasting with artificial neural networks: The state of the art. International Journal of Forecasting, 14(1), 35–62.
  • Breiman, L. (2001). Random forests. Machine Learning, 45(1), 5–32.
  • Burez, J., & Van den Poel, D. (2009). Handling class imbalance in customer churn prediction. Expert Systems with Applications, 36(3), 4626–4636.
  • Choi, H., & Varian, H. (2012). Predicting the present with Google Trends. Economic Record, 88, 2–9.
  • Chatfield, C. (2003). The Analysis of Time Series: An Introduction (6th ed.). Chapman & Hall/CRC.
  • De Gooijer, J. G., & Hyndman, R. J. (2006). 25 years of time series forecasting. International Journal of Forecasting, 22(3), 443–473.
  • Domingos, P. (2012). A few useful things to know about machine learning. Communications of the ACM, 55(10), 78–87.
  • Friedman, J. H. (2001). Greedy function approximation: A gradient boosting machine. Annals of Statistics, 29(5), 1189–1232.
  • Gardner, E. S. (1985). Exponential smoothing: The state of the art—Part II. International Journal of Forecasting, 1(4), 265–275.
  • Hansen, L. K., & Salamon, P. (1990). Neural network ensembles. IEEE Transactions on Pattern Analysis and Machine Intelligence, 12(10), 993–1001.
  • Hochreiter, S., & Schmidhuber, J. (1997). Long short-term memory. Neural Computation, 9(8), 1735–1780.
  • Hyndman, R. J., & Athanasopoulos, G. (2013). Forecasting: Principles and Practice. OTexts. (Online Book)
  • Makridakis, S., Wheelwright, S. C., & Hyndman, R. J. (1998). Forecasting: Methods and Applications. Wiley.
  • Rajkomar, A., Dean, J., & Kohane, I. (2017). Machine learning in medicine. The New England Journal of Medicine, 380, 1347–1358.
  • Ribeiro, M. T., Singh, S., & Guestrin, C. (2016). “Why should I trust you?”: Explaining the predictions of any classifier. In Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (pp. 1135–1144).
  • Taylor, J. W., & Letham, B. (2017). Prophet: Forecasting at scale. arXiv preprint arXiv:1703.11047.
  • Vapnik, V. N. (1998). Statistical Learning Theory. Wiley.
  • Zhang, G. P. (2003). Time series forecasting using a hybrid ARIMA and neural network model. Neurocomputing, 50, 159–175.

How to cite

Prof. (Dr) Sangeet Vashishtha (2025). Impact of Machine Learning on Drug Demand Forecasting in Pharmaceutical Supply Chains. International Journal of Research in All Subjects in Multi Languages, 13(4), 29-37. https://doi.org/10.63345/ijrsml.v13.i4.4

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This article is open access, published under the CC BY 4.0 licence. Copyright remains with the authors.